USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P56545 USC-OGP 2-DE database:  P56545 P56545 General information about the entry View entry in simple text format Entry name CTBP2_HUMAN Primary accession number P56545 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=C-terminal-binding protein 2; Short=CtBP2;. Gene name Name=CTBP2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1287: pI=6.52; Mw=25485 Cross-references UniProtKB/Swiss-Prot P56545; CTBP2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CTBP2_HUMAN Primary accession number P56545 Secondary accession number(s) A8K2X5 D3DRF5 O43449 Q5SQP7 Q69YI3 Q86SV0 Q9H2T8 Sequence was last modified on  July 15, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 170) Name and origin of the protein Description RecName: Full=C-terminal-binding protein 2; Short=CtBP2; Gene name Name=CTBP2 Encoded on Name=CTBP2 Keywords 3D-structure; Alternative splicing; Cell junction; Complete proteome; Differentiation; Direct protein sequencing; Host-virus interaction; Methylation; NAD; Nucleus; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome; Repressor; Synapse; Transcription; Transcription regulation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF016507; AAC39603.1; -; mRNA EMBL AF222711; AAG45951.1; -; mRNA EMBL BT007012; AAP35658.1; -; mRNA EMBL AK290390; BAF83079.1; -; mRNA EMBL AL833398; CAH10590.1; -; mRNA EMBL AL596261; CAH72472.1; -; Genomic_DNA EMBL AL731571; CAH72472.1; JOINED; Genomic_DNA EMBL AL731571; CAI16100.1; -; Genomic_DNA EMBL AL596261; CAI16100.1; JOINED; Genomic_DNA EMBL AL731571; CAI16102.1; -; Genomic_DNA EMBL CH471066; EAW49247.1; -; Genomic_DNA EMBL CH471066; EAW49250.1; -; Genomic_DNA EMBL CH471066; EAW49249.1; -; Genomic_DNA EMBL BC002486; AAH02486.1; -; mRNA EMBL BC047018; AAH47018.1; -; mRNA EMBL BC052276; AAH52276.1; -; mRNA EMBL BC072020; AAH72020.1; -; mRNA CCDS CCDS7643.1; -. [P56545-1]; . CCDS CCDS7644.1; -. [P56545-2]; . RefSeq NP_001077383.1; NM_001083914.2. [P56545-1]; . RefSeq NP_001277143.1; NM_001290214.2. [P56545-1]; . RefSeq NP_001277144.1; NM_001290215.2. [P56545-1]; . RefSeq NP_001307941.1; NM_001321012.1. [P56545-1]; . RefSeq NP_001307942.1; NM_001321013.1. [P56545-1]; . RefSeq NP_001307943.1; NM_001321014.1. [P56545-1]; . RefSeq NP_001320.1; NM_001329.3. [P56545-1]; . RefSeq NP_073713.2; NM_022802.2. [P56545-2]; . RefSeq XP_005269618.1; XM_005269561.2. [P56545-1]; . RefSeq XP_005269621.1; XM_005269564.2. [P56545-1]; . RefSeq XP_005269624.1; XM_005269567.2. [P56545-1]; . RefSeq XP_005269625.1; XM_005269568.4. [P56545-1]; . RefSeq XP_005269626.1; XM_005269569.2. [P56545-1]; . RefSeq XP_005269628.1; XM_005269571.2. [P56545-1]; . RefSeq XP_005269629.1; XM_005269572.3. [P56545-1]; . RefSeq XP_006717705.1; XM_006717642.2. [P56545-1]; . RefSeq XP_011537653.1; XM_011539351.1. [P56545-1]; . RefSeq XP_011537655.1; XM_011539353.1. [P56545-1]; . RefSeq XP_011537656.1; XM_011539354.1. [P56545-1]; . RefSeq XP_011537657.1; XM_011539355.1. [P56545-1]; . RefSeq XP_016871245.1; XM_017015756.1. [P56545-1]; . RefSeq XP_016871246.1; XM_017015757.1. [P56545-1]; . UniGene Hs.501345; -; . PDB 2OME; X-ray; 2.80 A; A/B/C/D/E/F/G/H=31-364 PDB 4LCJ; X-ray; 2.86 A; A/B/C/D/E/F/G/H=31-362 PDBsum 2OME; -; . PDBsum 4LCJ; -; . ProteinModelPortal P56545; -; . SMR P56545; -; . BioGrid 107870; 105; . DIP DIP-42104N; -; . IntAct P56545; 62; . MINT MINT-1188878; -; . STRING 9606.ENSP00000311825; -; . BindingDB P56545; -; . iPTMnet P56545; -; . PhosphoSitePlus P56545; -; . BioMuta CTBP2; -; . DMDM 3182976; -; . EPD P56545; -; . MaxQB P56545; -; . PaxDb P56545; -; . PeptideAtlas P56545; -; . PRIDE P56545; -; . DNASU 1488; -; . Ensembl ENST00000309035; ENSP00000311825; ENSG00000175029. [P56545-2]; . Ensembl ENST00000337195; ENSP00000338615; ENSG00000175029. [P56545-1]; . Ensembl ENST00000411419; ENSP00000410474; ENSG00000175029. [P56545-1]; . Ensembl ENST00000494626; ENSP00000436285; ENSG00000175029. [P56545-1]; . Ensembl ENST00000531469; ENSP00000434630; ENSG00000175029. [P56545-1]; . GeneID 1488; -; . KEGG hsa:1488; -; . UCSC uc001lie.5; human. [P56545-1]; . CTD 1488; -; . DisGeNET 1488; -; . GeneCards CTBP2; -; . HGNC HGNC:2495; CTBP2; . HPA CAB031916; -; . HPA HPA023559; -; . HPA HPA023564; -; . HPA HPA044971; -; . MIM 602619; gene; . neXtProt NX_P56545; -; . OpenTargets ENSG00000175029; -; . PharmGKB PA26996; -; . eggNOG KOG0067; Eukaryota; . eggNOG COG0111; LUCA; . GeneTree ENSGT00530000063021; -; . HOVERGEN HBG001898; -; . InParanoid P56545; -; . KO K04496; -; . OrthoDB EOG091G08GS; -; . PhylomeDB P56545; -; . TreeFam TF313593; -; . Reactome R-HSA-4641265; Repression of WNT target genes; . Reactome R-HSA-5339700; TCF7L2 mutants don't bind CTBP; . SignaLink P56545; -; . SIGNOR P56545; -; . ChiTaRS CTBP2; human; . EvolutionaryTrace P56545; -; . GeneWiki CTBP2; -; . GenomeRNAi 1488; -; . PRO PR:P56545; -; . Proteomes UP000005640; Chromosome 10; . Bgee ENSG00000175029; -; . CleanEx HS_CTBP2; -; . ExpressionAtlas P56545; baseline and differential; . Genevisible P56545; HS; . GO GO:0030054; C:cell junction; IEA:UniProtKB-KW; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0097470; C:ribbon synapse; IEA:Ensembl; . GO GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB; . GO GO:0003682; F:chromatin binding; IEA:Ensembl; . GO GO:0051287; F:NAD binding; IEA:InterPro; . GO GO:0016616; F:oxidoreductase activity; acting on the CH-OH group of donors; NAD or NADP as acceptor IEA:InterPro . GO GO:0003713; F:transcription coactivator activity; IEA:Ensembl; . GO GO:0003714; F:transcription corepressor activity; IEA:Ensembl; . GO GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc; . GO GO:0045892; P:negative regulation of transcription; DNA-templated; ISS:UniProtKB GO GO:0035563; P:positive regulation of chromatin binding; IEA:Ensembl; . GO GO:0048386; P:positive regulation of retinoic acid receptor signaling pathway; IMP:MGI; . GO GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI; . GO GO:0006351; P:transcription; DNA-templated; IEA:UniProtKB-KW GO GO:0019079; P:viral genome replication; TAS:ProtInc; . GO GO:0050872; P:white fat cell differentiation; ISS:UniProtKB; . Gene3D 3.40.50.720; -; 2; . InterPro IPR006139; D-isomer_2_OHA_DH_cat_dom; . InterPro IPR029753; D-isomer_DH_CS; . InterPro IPR006140; D-isomer_DH_NAD-bd; . InterPro IPR016040; NAD(P)-bd_dom; . Pfam PF00389; 2-Hacid_dh; 1; . Pfam PF02826; 2-Hacid_dh_C; 1; . SUPFAM SSF51735; SSF51735; 1; . PROSITE PS00671; D_2_HYDROXYACID_DH_3; 1; .

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